Episode 5: Introduction to Toxicology & Methemoglobinemia

In Part 1 of this episode, Elizabeth and Jocelyn go through a brief Introduction to Toxicology with the RRSIDEAD approach and common toxidromes, and in Part 2, Matthew and Elizabeth interview Dr Loo Kee Vooi about the exciting topic of Methemoglobinemia!
Thank you for listening!

Timestamps
Introduction to Toxicology
01:45 RRSIDEAD
05:55 MDAC (ABCDQ Mnemonic)
06:45 Dialyzable toxins (PLASMA TV) 
07:33 Antidote Quiz
10:11 Toxidromes
10:38 Sedative Hypnotic
11:08 Anticholinergic Toxidrome
11:46 Cholinergic Toxidrome (SLUDGE/DUMBBELLS)
13:38 Sympathomimetic Toxidrome
14:39 Serotonin Syndrome
15:28 Neuroleptic Malignant Syndrome
15:56 Malignant Hyperthermia

Methemoglobinemia 
18:47 Overview and Case Scenario 
20:24 Initial Management and Diagnostic Clues
23:17 Why is the SpO2 85%?
24:06: Common causes
25:06 Diagnosis
28:13 Considerations when giving Methylene Blue

Credits
Music: Life-line by Colorful Sound via Pixabay/ Best Day by Octosound via Pixabay 
SGH Podcast Studio
SEMS
Dr Mong Rupeng for reviewing the Introduction to Tox Segment 

References
https://litfl.com/approach-to-acute-poisoning/
https://emcrit.org/ibcc/methemoglobinemia/ 
Toxicology Handbook by Jason Armstrong/ Ovidiu Pascu (4th Ed) 
Goldfrank’s Toxicologic Emergencies (11th Ed) 

All recordings should not be taken by users/ audience as medical advice. Everyone is encouraged to see their physicians for proper medical consultation. 

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Chapters

• 1:45 RRSIDEAD
• 5:55 MDAC (ABCDQ Mnemonic)
• 6:45 Dialyzable toxins (PLASMA TV)
• 7:33 Antidote Quiz
• 10:11 Toxidromes
• 16:55 Part 2: Methemoglobinemia
• 18:47 Methb - Overview and Case Sce
• 20:24 Initial Management and Diagnostic Clues
• 23:17 Why is the SpO2 85%?
• 24:06 Common causes of Methb
• 25:06 Diagnosis
• 28:13 Considerations when giving Methylene Blue